ITMAT Information and Links

The Institute for the Translational Medicine and Therapeutics (ITMAT) is the academic home of the Center for Human Phenomic Science (CHPS). ITMAT supports research at the interface of basic and clinical research, with a particular focus on the development of new and safer therapeutic entities. ITMAT includes its own faculty and basic research space, CHPS (formerly the General Clinical Research Centers (GCRCs) at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia, and an expanding repertoire of cores, programs, and centers designed to support research endeavors between proof of concept in cellular and animal model systems across the translational divide into proof of concept and dose selection in humans. Educational programs relating to translational research, including a newly founded Masters in Translational Research, are also housed within ITMAT.

The objectives of ITMAT are:

  • to provide an intellectual home and core critical mass for those who pursue translational research;
  • to expand the number of faculty pursuing translational research at Penn through direct recruitment and enhancement of recruitment packages of any academic entity;
  • to expand this critical mass by education of existing faculty in translational research and
  • to a single point of contact for Penn investigators seeking information and support to pursue translational research and for outside agencies wishing to engage with Penn in this area.

ITMAT includes investigators focused on clinical and translational research in all schools at Penn, the Children's Hospital of Philadelphia, the Wistar Institute, and the University of Sciences in Philadelphia. These partner institutions are joined by the Clinical and Translational Science Award (CTSA) funded under the NIH Roadmap, designating ITMAT as the academic home for the program.